Preventive & Longevity
Extended annual exams, advanced cardiac screening, cancer early detection, metabolic optimization.

Trusted by members for 20 years to coordinate their care, advocate for them, and guide every aspect of their health and well-being.
Signature Medicine is a locally physician-owned concierge internal medicine practice in Newtown, PA, founded by Dr. Ashish Sitapara in 2005 and capped at 300 patients.
At Signature Medicine, we limit our practice to 300 patients. That's it. The result is care that feels like it should—personal, thorough, and always available.
We handle specialists, hospitals, insurance battles, and follow-ups. Nothing falls through the cracks because we quarterback your entire care. This is what sets us apart from every other concierge practice.
Call, text, or email—nights, weekends, holidays. A real person who knows you answers, not a call center.
No phone trees. Ever.Sick today? Seen today. Not next week. Not urgent care with a stranger. Your doctor, same day.
Average wait: hours, not weeks30 to 60 minutes. As long as you need. Time to actually talk, investigate, and solve problems together.
We schedule time for listening
Founder & Board Certified Internist
After teaching at Harvard Medical School and the University of Pennsylvania, Dr. Sitapara had a choice: join a large practice and see 30 patients a day, or build something different.
He chose different.
In 2005, he founded Signature Medicine with one idea: what if a doctor actually had time to know their patients? Twenty years later, many of his original patients are still with him—and have trusted him with the care of their parents, children, and friends.
Your annual membership unlocks access to every care pathway—from prevention to urgent care to specialized treatment. No surprise bills. No nickel-and-diming.
Extended annual exams, advanced cardiac screening, cancer early detection, metabolic optimization.
GLP-1 medications (Ozempic, Wegovy, Zepbound). Physician-supervised. FDA-approved only.
Menopause care, hormone optimization, thyroid management, bone density screening.
Testosterone evaluation, prostate health, cardiovascular risk assessment, sexual health.
Sick today? Seen today. After-hours access. Rapid labs. Direct prescriptions.
If hospitalized, Dr. Sitapara coordinates with your team and manages your transition home.

Most new members come to us through referrals from members who already trust us.
“I finally have a doctor who actually listens. The peace of mind is worth every penny. When I call, someone who knows me answers—not a call center, not a voicemail tree.
“When my mother needed surgery, Dr. Sitapara coordinated everything—the specialist, the hospital, the follow-up care. He was our quarterback through the whole process. I never had to chase anyone down.
“When I needed urgent care on a Saturday, Dr. Sitapara called me back within minutes. Try getting that anywhere else. Twenty years later, my whole family sees him now.
Signature Medicine is not MDVIP, not a hospital system, and not private equity. We're 100% locally owned by Dr. Sitapara. Your membership fee supports your care—not corporate overhead or franchise royalties. See the side-by-side comparison →
As members of the Private Physicians Alliance, you also have access to like-minded concierge physicians nationwide if you travel. New to the model? Read our complete guide to concierge medicine in Bucks County.
In a typical primary care practice in Bucks County, your doctor cares for 2,000–3,000 patients, visits are 15 minutes, and you reach the office through a phone tree. At Signature Medicine, Dr. Sitapara caps his panel at 300 patients, visits run 30–60 minutes, and members reach him directly 24/7. The annual membership fee also funds total care coordination — we manage specialists, hospitals, insurance, and follow-up so nothing falls through the cracks.
Unlike MDVIP and other franchise concierge practices, Signature Medicine is locally physician-owned. Our key differentiator is total care coordination: we quarterback your entire healthcare — coordinating specialists, hospitals, insurance, and follow-ups. Your membership fee stays local and decisions are made by your doctor, not corporate.
Care coordination is our specialty. We act as your healthcare quarterback — managing referrals to specialists, communicating with hospitals, handling insurance pre-authorizations, following up on test results, and ensuring nothing falls through the cracks.
Yes. The annual membership fee covers enhanced access and coordination services. For office visits, labs, and procedures, we bill your insurance as usual. Most patients find their out-of-pocket costs are similar to — or less than — traditional practices because of our preventive approach.
We serve patients throughout Bucks County, PA including Newtown, Yardley, Langhorne, Doylestown, Washington Crossing, New Hope, and surrounding areas. Some members drive from Philadelphia and Princeton for Dr. Sitapara's care.
Dr. Sitapara limits his practice to approximately 300 patients, compared to 2,000–3,000 in a typical practice. This allows for 30–60 minute appointments and the time to truly coordinate all aspects of your care.
Dr. Ashish Sitapara completed his fellowship at Boston University Medical Center. He taught at Harvard Medical School and the University of Pennsylvania, where he helps teach the "Good Doctoring" course. He is board-certified in Internal Medicine and is a Fellow of the American College of Physicians (FACP).
Schedule a complimentary consultation to learn if Signature Medicine membership is right for you and your family.
Or call us directly: (215) 968-4804