Signature Medicine is a member of the Private Physicians Alliance — a national federation of independent, physician-owned concierge practices. Membership gives you preferred access to the most advanced patient-facing services in modern medicine, with Dr. Sitapara as the ordering and interpreting physician.
Independent practices like Signature Medicine pool negotiating power through the Private Physicians Alliance so members can access advanced screening, genomics, sleep medicine, and global medical-travel services at preferred-member terms — without a corporate franchise filtering the list.
Each partner below is unlocked through Signature Medicine’s PPA membership. Pricing and clinical fit are discussed during your consultation — the practice itself stays the constant.
Whole-body MRI screening that looks for early-stage disease before symptoms appear.
Prenuvo is a same-day, radiation-free MRI scan of the head, neck, spine, chest, abdomen, and pelvis. It is designed to detect more than 500 conditions — including many solid tumors at stage I — years before they would surface in a standard physical.
A single blood test that screens for a shared cancer signal across more than 50 types of cancer.
Galleri is a multi-cancer early detection (MCED) test from Grail. It looks for DNA methylation patterns in cell-free DNA that are shared across dozens of cancers — including many that have no recommended screening at all today (pancreatic, ovarian, esophageal, liver).
Clinical-grade genetic testing across hereditary cancer risk, prenatal screening, and tumor-informed cancer monitoring.
Natera operates one of the most clinically validated genetic-testing platforms in the country — Signatera for tumor-informed minimal-residual-disease monitoring after a cancer diagnosis, Empower for hereditary cancer risk, Panorama for prenatal screening, Horizon for carrier screening, and Renasight for kidney disease. Each is a different decision support tool, not a wellness kit.
Clinical whole-genome analysis — one sample, sequenced once, re-queried for the rest of your life.
MyOme is a clinical-grade whole-genome platform. Unlike consumer ancestry kits, the data is generated under CLIA/CAP standards and is designed to be re-interrogated as new clinical evidence emerges — drug-response (pharmacogenomics), inherited cancer risk, cardiovascular risk, carrier status for family planning.
Clinical genomics built for adult preventive medicine — cardiovascular risk, pharmacogenomics, and inherited disease.
New Amsterdam Genomics provides clinician-ordered genomic testing focused on actionable findings for adults: polygenic risk for cardiovascular disease, pharmacogenomic guidance on common prescriptions, and monogenic risk for conditions where early detection changes the plan.
At-home sleep apnea diagnostics and treatment without a sleep-lab referral or insurance maze.
Empower Sleep delivers FDA-cleared home sleep tests (WatchPAT-style devices), board-certified sleep physician interpretation, and CPAP / oral-appliance treatment plans — all coordinated remotely. Most patients move from "I think I might have apnea" to a treatment plan in days, not months.
Clinical-grade body composition analysis — muscle mass, visceral fat, segmental analysis — in under a minute.
InBody uses multi-frequency bioelectrical impedance to measure skeletal muscle mass, body-fat percentage, visceral fat area, segmental lean balance, and total body water. It is the standard tool used by sports medicine, weight-management programs, and geriatrics to track what actually changes when a plan is working — because BMI cannot tell you whether you’re losing fat or losing muscle.
Hospital-to-hospital medical evacuation membership that gets you home to the hospital you choose.
Standard travel insurance moves you to the "nearest appropriate facility." Medjet is different: if you are hospitalized more than 150 miles from home anywhere in the world, Medjet arranges and pays for transport back to the hospital you pick. The service has been operating for 30 years and works with roughly 50 global air-ambulance providers, coordinated 24/7 from Birmingham, Alabama.
Partner roster expands as the Private Physicians Alliance adds vetted partnerships. Dr. Sitapara only surfaces a partner when it fits your specific care plan — none of these are upsells.
MDVIP is a national franchise: physicians pay royalties and follow corporate protocols, and the patient-facing partner list is whatever the parent company negotiates. Signature Medicine is owned by Dr. Sitapara and federated with peer practices through the Private Physicians Alliance — so the partner list grows because independent physicians vet what actually helps their patients.
Signature Medicine is owned by Dr. Sitapara, not a franchise corporation or private-equity rollup.
The Private Physicians Alliance pools negotiating power across independent practices nationwide.
Every partner above is reviewed by practicing PPA physicians before it’s offered to members.
MDVIP is a national franchise — physicians pay royalties and follow corporate protocols, and patient-facing partnerships are limited to what the parent company negotiates. Signature Medicine is independent and a member of the Private Physicians Alliance (PPA), a federation of physician-owned practices that pools negotiating power. Through PPA we unlock direct, preferred access to partners like Prenuvo, Galleri, Natera, MyOme, New Amsterdam Genomics, Empower Sleep, InBody, and Medjet — without a corporate intermediary deciding which services count.
No — the partner services themselves are billed by the partner. What your Signature Medicine membership gives you is preferred-member access, the clinical coordination, and Dr. Sitapara as the ordering and interpreting physician. The annual fee covers the relationship and the practice services described on the Membership page; partner pricing is disclosed during your consultation.
No. These are options, not requirements. Most members use a few — usually whichever fits their goals (longevity screening, travel safety, sleep optimization). Some use all of them; some use none. The point of the membership is the physician relationship; these benefits are what that relationship can unlock when you want them.
Yes, if they are also Signature Medicine members. Each partner sets its own eligibility — most are individual offerings, some have family pricing (Medjet, for example). Dr. Sitapara walks you through the specifics during a consultation.